The Apaf-1-binding protein Aven is cleaved by Cathepsin D to unleash its anti-apoptotic potential
نویسندگان
چکیده
منابع مشابه
APAF 1 ( Apoptotic protease activating factor 1 )
Five isoforms of APAF1 cDNA have been identified in Homo sapiens: The original APAF1 (also called Apaf-1S) is 3585 bp long (it contains 12 WD40 repeats); The APAF1-1M isoform (3618 bp) contains an insertion of 33 nt after position 295 of the first published sequence (11 aa insertion GKDSVSGITSY between aa 98 and 99; it also contains 12 WD40 repeats); The APAF1XS isoform (3516 bp) contains the s...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2012
ISSN: 1350-9047,1476-5403
DOI: 10.1038/cdd.2012.17